ClearSight Therapeutics
Advancing the Next Generation of OTC Eye Care
- Developing next-generation ophthalmic products designed to relieve dryness, irritation, and ocular discomfort—within established FDA OTC monograph pathways.
ClearSight is focused on developing smarter solutions to common eye conditions. We’re on a mission to disrupt the sleepy over-the-counter (OTC) eye care industry with a novel and innovative portfolio of products.
THE PROBLEM:
Three conditions. Tens of millions affected. Billions lost every year. A problem that wont blink.
Millions of people experience eye discomfort every day—from dryness and irritation to redness and lens-related discomfort. ClearSight Therapeutics is focused on expanding access to effective, over-the-counter solutions that support ocular surface comfort and eye health.
Our products are designed to align with FDA OTC ophthalmic monograph requirements while addressing large, underserved consumer eye care needs.
THE SOLUTION:
CS-001 is ClearSight’s proprietary ophthalmic formulation platform engineered to optimize ocular surface lubrication and moisture retention.
Developed using a structured excipient system designed to support tear film performance, CS-001 enhances surface wetting and helps maintain hydration across the ocular surface.
The result is soothing, sustained comfort and temporary relief of burning and irritation due to dryness—delivered within established FDA OTC ophthalmic monograph parameters.
THE SOLUTION:
CS-001 Ocular Surface Lubrication System
- Anti-Bacterial Efficacy*
- Anti-Viral Efficacy*
- Anti-Fungal Efficacy*
Dry Eye Treatment
Rewetting Drops
Contact Lense Rewettng
Disclaimer: All images, renderings, and visual representations of our eye drop products are conceptual and may not reflect the final design.
eye condition In-sights
Common eye conditions are a daily cause of pain and discomfort for millions of people
Dry Eye Disease
Patients with dry eyes report 30% lower work productivity, especially in screen-heavy environments.
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Current OTC Options:
Artificial Tears and Lubricants
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Key Unmet Need(s):
Low-cost Biofilm treatment
Contact Lens Rewetting
More than 1 in 5 wearers interrupt their day to remove or adjust lenses due to dryness.
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Current OTC Options:
Active lens cleaning
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Key Unmet Need(s):
Low-cost Biofilm treatment
Infection prevention
Acute Infectious Conjunctivitis (Pink eye)
Something that can really ruin your day, Pink Eye, (conjunctivitis) alone affects up to 6 million people in the U.S.
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Current OTC Options:
Only Rx Antibiotics
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Key Unmet Need(s):
OTC option
Anti-viral Treatment
The Science Behind CS-001
Designed for Ocular Surface Comfort
The ocular surface relies on a stable tear film to maintain comfort and visual clarity. Disruptions in moisture can lead to symptoms such as burning, irritation, redness, and discomfort
CS-001™ is formulated to enhance lubrication and support surface moisture retention through a carefully balanced demulcent and excipient system.
Formulation Strategy
CS-001™ is designed to:
- Enhance surface wetting
- Promote even distribution across the ocular surface
- Support tear film lubrication
- Provide sustained soothing comfort
Platform Versatility
Because CS-001™ is a modular lubrication platform, it supports development across multiple OTC eye care categories, including
- Dry eye relief
- Contact lens comfort
- Redness & irritation relief
About ClearSight Therapeutics
OUR HISTORY
ClearSight Therapeutics was founded in 2023 by a team of eye care industry veterans and partners to develop better solutions to common eye conditions which continue to disrupt the lives of millions of patients.
OUR values
At ClearSight Therapeutics, we are committed to ethical and responsible biotech research and development. We believe in putting patients first, and we are dedicated to developing OTC eye treatments that are safe, effective, and accessible to all.
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OUR PARTNERS
Health Wildcatters was founded in 2013 to address the need for a health innovation hub in the burgeoning Dallas/Fort Worth Metroplex healthcare industry. Since its inception the Health Wildcatters portfolio has grown to 118 startups who have raised over $350 million. Health Wildcatters provides a seed investment, in-kind perks, and a vast network of mentors comprised of well over 200 individuals spanning the healthcare industry, professional services, and many other verticals.
A nonprofit, MassChallenge connects startups, experts, corporations, and communities to grow and transform businesses and economies. Our unique equity-free model allows us to accelerate high-impact startups with bold, disruptive ideas from non-traditional backgrounds.
We offer a variety of programs, accelerators, and partnerships throughout the year to those who share our vision of transformative innovation.
The center of gravity for entrepreneurs outside of Silicon Valley Thousands of entrepreneurs, programmers and designers gather day and night, in-person and online for meetups, classes and coworking. With boots on the ground in Austin, Dallas, Houston, San Antonio, and Washington, DC we meet the best entrepreneurs outside of Silicon Valley and introduce them to investors, employees, and customers. According to Pitchbook, Capital Factory has been the most active investor in Texas since 2010.